Supplement Label Index

Ingredient Pairings

Chondroitin Sulfate and Glucosamine are declared together 35.46x more often than chance would predict, among 75,838 on-market DSLD products.

For every pair of compounds we track, we compare how often they're actually declared on the same label to how often you'd expect by chance alone, given how common each one is on its own. A pair with a lift of 3x shows up on the same label three times as often as random chance would predict; a lift below 1x means the pair actually avoids each other, more often found on separate products than together. Only pairs declared together on at least 100 products are included, to keep small-sample noise out of the rankings.

Most disproportionate pairings

The pairs that travel together far more than their individual popularity alone would explain — the closest thing DSLD data has to visible "stacks."

Chondroitin Sulfate + Glucosamine 35.5x Chlorella + Spirulina (Arthrospira platensis) 28.0x Lutein + Zeaxanthin 24.0x Chondroitin Sulfate + Methylsulfonylmethane (MSM) 23.4x Glucosamine + Methylsulfonylmethane (MSM) 20.6x Chondroitin Sulfate + Hyaluronic Acid 18.5x Beta-Alanine + L-Citrulline 17.5x Collagen (Hydrolyzed Collagen Peptides) + Hyaluronic Acid 17.3x Lutein + Lycopene 17.2x Lycopene + Zeaxanthin 17.1x Astaxanthin + Zeaxanthin 14.8x Glycine + L-Lysine 14.4x
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PairLiftTogether% of A's products% of B's products
Chondroitin Sulfate + Glucosamine 35.46x 995 80.6% 57.7%
Chlorella + Spirulina (Arthrospira platensis) 28.02x 1,016 67.9% 55.3%
Lutein + Zeaxanthin 23.98x 1,172 47.0% 78.9%
Chondroitin Sulfate + Methylsulfonylmethane (MSM) 23.45x 667 54.0% 38.2%
Glucosamine + Methylsulfonylmethane (MSM) 20.56x 816 47.4% 46.7%
Chondroitin Sulfate + Hyaluronic Acid 18.52x 333 27.0% 30.2%
Beta-Alanine + L-Citrulline 17.54x 1,548 60.5% 59.2%
Collagen (Hydrolyzed Collagen Peptides) + Hyaluronic Acid 17.3x 410 25.2% 37.1%
Lutein + Lycopene 17.19x 1,203 48.2% 56.6%
Lycopene + Zeaxanthin 17.15x 714 33.6% 48.1%
Astaxanthin + Zeaxanthin 14.77x 310 28.9% 20.9%
Glycine + L-Lysine 14.39x 568 36.0% 30.0%
Hyaluronic Acid + Methylsulfonylmethane (MSM) 14.08x 358 32.4% 20.5%
Beta-Alanine + Creatine 13.59x 899 35.1% 45.9%
Beta-Alanine + Caffeine 12.97x 1,876 73.3% 43.8%
Glucosamine + Hyaluronic Acid 11.24x 282 16.4% 25.5%
Choline + Inositol (myo-Inositol) 10.79x 3,412 62.6% 77.5%
L-Arginine + L-Lysine 10.74x 785 26.9% 41.4%
Beta-Alanine + L-Tyrosine 10.68x 1,232 48.1% 36.0%
Creatine + L-Citrulline 10.31x 697 35.6% 26.6%
Chondroitin Sulfate + Collagen (Hydrolyzed Collagen Peptides) 10.15x 269 21.8% 16.5%
Lycopene + Saw Palmetto (Serenoa repens) 10.02x 450 21.2% 28.1%
Lycopene + Molybdenum 9.97x 1,286 60.5% 28.0%
Astaxanthin + Lycopene 9.95x 299 27.9% 14.1%
Caffeine + L-Citrulline 9.92x 1,467 34.2% 56.1%
Milk Thistle (Silybum marianum) + N-Acetylcysteine (NAC) 9.66x 439 19.7% 28.3%
Boron + Molybdenum 9.52x 2,342 57.7% 50.9%
Manganese + Molybdenum 9.41x 4,251 57.1% 92.4%
Glycine + L-Arginine 9.37x 570 36.1% 19.5%
Glycine + L-Glutamine 9.23x 558 35.3% 19.2%

Most common pairings

Ranked by raw count instead of lift — mostly multivitamin and B-complex staples that are common individually, so their high overlap isn't necessarily surprising.

PairTogetherLift
Vitamin B12 (Cobalamin) + Vitamin B6 (Pyridoxine) 12,063 4.17x
Vitamin B12 (Cobalamin) + Folate (Vitamin B9) 10,613 4.78x
Vitamin B6 (Pyridoxine) + Folate (Vitamin B9) 10,471 4.39x
Niacin (Vitamin B3) + Vitamin B6 (Pyridoxine) 10,377 4.18x
Vitamin B6 (Pyridoxine) + Vitamin C 10,153 2.55x
Calcium + Magnesium 10,078 2.63x
Vitamin C + Zinc 9,887 2.84x
Vitamin B12 (Cobalamin) + Niacin (Vitamin B3) 9,874 4.27x
Vitamin A + Vitamin C 9,862 3.32x
Vitamin B12 (Cobalamin) + Vitamin C 9,558 2.57x
Calcium + Vitamin C 9,507 1.85x
Pantothenic Acid (Vitamin B5) + Vitamin B6 (Pyridoxine) 9,393 4.63x
Calcium + Potassium 9,365 2.94x
Thiamine (Vitamin B1) + Vitamin B6 (Pyridoxine) 9,284 4.63x
Riboflavin (Vitamin B2) + Vitamin B6 (Pyridoxine) 9,270 4.61x
Vitamin C + Vitamin E 9,083 2.96x
Thiamine (Vitamin B1) + Riboflavin (Vitamin B2) 9,060 6.98x
Calcium + Vitamin D 8,947 2.28x
Thiamine (Vitamin B1) + Vitamin B12 (Cobalamin) 8,933 4.78x
Thiamine (Vitamin B1) + Niacin (Vitamin B3) 8,911 5.56x

Pairs that avoid each other

The other direction: compounds that show up on the same label less often than chance would predict — often a sign they belong to different product categories (a stimulant-focused pre-workout vs. a basic multivitamin, for instance) rather than any real incompatibility.

PairLiftTogether
Caffeine + Iron 0.22x 109
L-Citrulline + Zinc 0.23x 108
Beta-Alanine + Zinc 0.26x 116
Caffeine + Vitamin A 0.26x 165
Caffeine + Manganese 0.27x 112
L-Citrulline + Vitamin D 0.28x 146
Caffeine + Selenium 0.28x 123
Beta-Alanine + Vitamin D 0.3x 152
L-Citrulline + Riboflavin (Vitamin B2) 0.31x 106
Caffeine + Zinc 0.32x 240
Omega-3 Fatty Acids (EPA + DHA) + Potassium 0.35x 254
Caffeine + Vitamin E 0.35x 233
Creatine + Vitamin A 0.35x 104
Caffeine + Vitamin D 0.36x 308
Melatonin + Zinc 0.36x 103