Vitamin B12 (Cobalamin)
Of 14,303 on-market vitamin b12 (cobalamin) products in the January 2026 DSLD dump, the median declared dose is 35 mcg, and 66.7% list Cyanocobalamin as the primary form.
Form share
Of 13,939 products with an identifiable primary form, here is the share held by each form of Vitamin B12 (Cobalamin) on the market today.
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| Form | Quality tier | n | Share |
|---|---|---|---|
| Cyanocobalamin | Tier 1 | 9,291 | 66.7% |
| Methylcobalamin | Tier 1 | 4,621 | 33.2% |
| Adenosylcobalamin | Tier 1 | 27 | 0.2% |
Form share over time
Entry-year breakdown of the top forms, 2012–2025.
Dose distribution
Deciles of declared dose per serving (mcg), among 14,041 products with a disclosed amount, against the RDA of 2.4.
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- 0.7% of products fall below the fairy-dust threshold (0.5 mcg, 20% of the studied low dose).
- 0.4% of products don't disclose an amount because Vitamin B12 (Cobalamin) is declared inside a proprietary blend.
Where does your dose rank?
Enter a per-serving dose (mcg) to see exactly how it compares to the 14,041 on-market vitamin b12 (cobalamin) products with a disclosed amount. The chart above groups doses into deciles; this looks up the exact percentile for one number.
By dosage form
By target group
Top brands
| Brand | Products |
|---|---|
| Douglas Laboratories | 292 |
| DC | 193 |
| Centrum | 185 |
| Cellucor | 174 |
| Nature Made | 151 |
| Wonder Laboratories | 149 |
| Nature's Way | 142 |
| Source Naturals | 135 |
| MegaFood | 125 |
| Emergen-C | 121 |
| Life Extension | 119 |
| The Vitamin Shoppe | 110 |
| NOW | 105 |
| Metagenics | 103 |
| Pure Encapsulations | 101 |
| Solgar | 100 |
| New Chapter | 98 |
| Country Life | 97 |
| Puritan's Pride | 94 |
| Higher Nature | 94 |
| Vitamin World | 92 |
| XYMOGEN | 90 |
| Bayer One A Day | 89 |
| Bluebonnet | 88 |
| GNC Mega Men | 85 |
Search interest over time
How often people search for vitamin b12 (cobalamin) on Google, US only, the last 5 years. This is public interest, not DSLD label data — a spike here doesn't necessarily line up with anything on this page, and Google's own index (100 = that term's peak popularity in the chosen window) is relative, not an absolute search-volume count.
Or see this search directly on trends.google.com.
Forms explained
Most extensively clinically studied form (basis of the pivotal dose-finding trial and most deficiency-treatment literature); a 2015 review found no evidence that the "coenzyme" forms are actually superior for preventing/treating deficiency.
Source: Eussen SJ et al. 2005, Arch Intern Med 165(10):1167-1172, PMID 15911731; Obeid R et al. 2015, Mol Nutr Food Res 59(7):1364-1372, PMID 25820384
One of the two naturally active intracellular coenzyme forms, but per the same 2015 review there is no strong evidence it is clinically superior to cyanocobalamin for correcting deficiency. A commonly repeated "3x greater tissue retention" marketing claim (attributed to a 2015 journal study) could NOT be traced to any real paper -- treat as unverifiable/likely fabricated, not fact.
Source: Obeid R et al. 2015, PMID 25820384
The other naturally occurring coenzyme form, same rationale as methylcobalamin -- a genuine coenzyme form but not shown superior to cyanocobalamin for standard deficiency correction. "Dibencozide" is simply a synonym/brand name for this same molecule.
Source: Obeid R et al. 2015, PMID 25820384
Reference values
- RDA (adult): 2.4 mcg
- Tolerable Upper Intake Level (adult): not established — Confirmed not established -- low potential for toxicity; the body does not store meaningful excess, and no adverse effects have been associated with high B12 intake from food or supplements in healthy individuals, including in high-dose intervention trials.
- Studied clinical dose range: 2.5–1000 mcg
- Eussen SJ et al. 2005, Arch Intern Med 165(10):1167-1172, PMID 15911731 -- dose- finding RCT (n=120) of 2.5/100/250/500/1000mcg/day oral cyanocobalamin x16wk in older people with mild B12 deficiency; plasma methylmalonic acid fell 16/16/23/33/33%; doses of 647-1032mcg/day gave 80-90% of the maximal MMA reduction.
- Note: A widely-repeated marketing claim that methylcobalamin has "3x greater tissue retention" than cyanocobalamin, attributed to a "2015 Journal of Clinical Pharmacology" study, could not be traced to any real paper -- treat as unverifiable/ likely-fabricated marketing content, not fact. See forms.yaml.