Caffeine Citrate

Caffeine Citrate is a tier 2 form of Caffeine, used in 188 on-market products and providing 50.3% elemental caffeine by weight.

Why this tier: Well-established in neonatal medicine (apnea of prematurity) as a distinct clinical use-case; in adult supplements it is primarily a solubility/stability choice delivering the same caffeine molecule, with no evidence of a meaningfully different adult efficacy/safety profile per mg of caffeine. Caffeine citrate is only ~50.3% caffeine by mass (1:1 caffeine:citric acid, MW 386.31), the standard clinical equivalence being 20 mg/mL caffeine citrate = 10 mg/mL caffeine base, so declared mg of the salt over-counts caffeine about 2x.

Trend

Brands using this form