Benfotiamine (fat-soluble synthetic prodrug)
Benfotiamine (fat-soluble synthetic prodrug) is a unrated form of Thiamine (Vitamin B1), used in 0 on-market products .
0
on-market products
unrated
quality tier
n/a
elemental fraction
Basis: A different prodrug molecule, not a salt of thiamine itself
Why this tier: Early trials suggested neuropathy-symptom benefit, but longer/larger trials (BOND 12-month, 24-month T1D) found no significant benefit on nerve function despite good tolerability -- superior-bioavailability claims are not settled.
Source: Stracke H et al. 2008 (BENDIP), Exp Clin Endocrinol Diabetes 116(10):600-5, PMID 18473286; Fraser DA et al. 2012, Diabetes Care 35(5):1095-7, PMID 22446172 (24-month T1D, n=67); Ziegler D et al. 2026 (BOND), BMJ Open Diabetes Res Care 14(1):e005773, PMID 41571333
Brands using this form
No on-market brand data available.