Standardized root extract, >=5% withanolides (KSM-66-type)

Standardized root extract, >=5% withanolides (KSM-66-type) is a tier 1 form of Ashwagandha (Withania somnifera), used in 113 on-market products .

Typical standardization: >=5% withanolides, root-only, aqueous extraction

Why this tier: This is the material used in the Chandrasekhar 2012 RCT (n=64) and several other small RCTs -- among the most extensively studied commercial ashwagandha forms, though NIH ODS describes ashwagandha trials overall as fairly small.

Source: Chandrasekhar K et al. 2012, Indian J Psychol Med 34(3):255-262, PMID 23439798

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