Supplement Label Index

Citrulline Malate (2:1) vs. L-Citrulline Aspartate

Among 1,225 on-market l-citrulline products with an identifiable primary form, 84.7% use Citrulline Malate (2:1) (1,037 products) and 10.4% use L-Citrulline Aspartate (128).

Citrulline Malate (2:1)L-Citrulline Aspartate
Quality tierUnratedUnrated
L-Citrulline by weight72.3%56.8%
Share of market84.7%10.4%
On-market products1,037128
Median declared dose2,892 mg
middle half: 1,084.5–4,338
284 mg
middle half: 284–284
Most common brandsCellucor, XTEND, DAS LabsPS ProSupps, ProSupps

Doses are declared per serving in mg. “By weight” is the share of the ingredient that is the nutrient itself (e.g. elemental magnesium in a magnesium salt).

Why Citrulline Malate (2:1) is unrated

The form used in the cited exercise trials (6-8g), but no study showing an advantage for citrulline malate over free L-citrulline exists: in one randomized crossover at matched citrulline dose (5.3 g), neither form improved neuromuscular performance (Martin-Olmedo 2025). The Trexler meta-analysis itself flags the form of citrulline as an unexplored moderator.

Source: Perez-Guisado J, Jakeman PM 2010, J Strength Cond Res 24(5):1215-22, PMID 20386132; Bendahan D et al. 2002, Br J Sports Med 36(4):282-9, PMID 12145119; Trexler ET et al. 2019, PMID 30895562; Martin-Olmedo JJ et al. 2025, Int J Sport Nutr Exerc Metab 35(2):89-98, PMID 39662304

Why L-Citrulline Aspartate is unrated

No head-to-head human bioavailability or efficacy comparison of this form was located in PubMed searches.

Tiers summarize published comparative bioavailability or outcome evidence for each form (see methodology). This page describes the market; it is not a recommendation to take either form. Talk to a clinician about what's right for you.

Other l-citrulline comparisons